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BRAGGSS information for hospitals

Participants can be eligible for both the BRAGGSS (Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate) and BSRBR-RA studies at the same time.

Researcher in the lab

Both studies collect data from participants with rheumatoid arthritis starting treatment with a biologic or biosimilar therapy.

The studies have some differences (for example, BRAGGSS collect a blood sample from each participant where the BSRBR-RA does not) but as the clinical information collected for BRAGGSS and BSRBR-RA is very similar, a linked route has been set up for participants who are eligible to take part in both studies.

This minimises the amount of paperwork while allowing us to collect the data we need without imposing further on the time of our participants and their consultants and nurses. 

If a participant is eligible for both the BRAGGSS and the BSRBR-RA study, they can be recruited via the linked route.

This means that once the participant has consented to be involved in both studies, only one set of baseline documents and subsequent follow-up questionnaires needs to be completed.

For more information on how to recruit via the linked route, please contact the BRAGGSS team who are coordinating this:

Tel: +44 (0)161 275 5596

By registering the participant in this way, it means that they will be included in the accrual figures for both studies.

Pre-biologic/biosimilar start date

Recruited to BRAGGSS and BSRBR-RA

Arrow pointing to the right

Accrual uploaded for BRAGGSS study

Downward-pointing arrow

Downward-pointing arrowIf bio start date confirmed on BRAGGSS 3 month follow up the patient is then added to BSRBR-RA database*.

BRAGGSS 3 month follow up

Biologic/biosimilar therapy start date confirmed

Arrow pointing to the right

Accrual uploaded for BSRBR-RA study

* This will be a minimum of 3 months after the biologic start date, which is confirmed on the BRAGGSS 3 month follow-up. Accruals are uploaded on a monthly basis.

If you want to know if your patient is already registered with the BSRBR-RA or if they have been included in the BSRBR-RA accrual upload, please contact the team on 0161 275 1652/7390.


If a patient is registered with the BSRBR-RA via the linked route and is subsequently withdrawn from BRAGGSS, the patient’s registration and follow up with the BSRBR-RA will continue unless we are notified directly by the registering site or the patient to request withdrawal from the BSRBR-RA.